IgG Index and Synthesis *

SIM

LAB555

CPT

Synonyms

IgG Synthesis rate; CSF IgG Synthesis; IgG Synthesis; Spinal fluid IgG Synthesis; CNS IgG Synthesis  

Specimen Type

CSF and blood 

Container

Red-top or gold-top tube and sterile (CSF)container

Collection Instructions

Spinal Tap; Blood must be collected when CSF obtained or within 24 hours

Volume

Volume: 1.5 ml serum and 1 mL CSF 
Min. volume: 0.7 serum and 0.5 mL CSF

Additional Information

Both serum and CSF must be sent at same time

Patient Preparation

Specimen Processing Instructions

Separate serum from cells if using red-top tube

Transport Requirements

Room Temperature

Specimen Stability

14 days 

Rejection Criteria

Blood in CSF;  quantity not sufficient; both specimens not received

Reference Range

Reference range accompanies report.

Critical Value

Test Includes

IgG and albumin quantitation in both serum and spinal fluid. The calculation of IgG synthesis rate in the central nervous system 

Methodology

CSF IgG, CSF albumin, and serum IgG: immunologic; serum albumin: spectrophotometry; synthesis rate by calculation 

Testing Frequency

LCA

203836 

Reviewed By

Rhonda Crowe   

Reviewed Date

2/24/23

Supplemental

* Denotes Reference Lab Test