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Clinical Research Trials

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(-) Breast Cancer
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Status

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Disease Site

Oncology
Symptom Management & Cancer Control
(-) Breast Cancer
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Study Type

Treatment

Oncology

Breast Cancer

A Phase IIR/III Trial of Standard of Care Therapy With or Without Stereotactic Body Radiotherapy (SBRT) and/or Surgical Ablation for Newly Oligometastatic Breast Cancer (NGR BR002)
Closed
A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo (NSABP B-59)
Closed
A Randomized, Double-Blind, Phase III Trial of Paclitaxel/ Trastuzumab/ Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer (NRG-BR004)
Closed
Advanced Breast Cancer (A5481082)
Closed
Breast Cancer Survivors, Cognitive Impairment, (REMEMBER) (WF 97116)
Complete
Breast or Gynecologic Cancer, Improving Sexual Desire (NRG-CC004)
Closed
Breast Cancer, Young Women, Pregnancy Outcomes (POSITIVE) (A221405)
Complete
HER2 Negative Primary Breast Cancer, gBRCA1/2 Mutations and High Risk (NSABP B-55)
Closed
High-Risk; Hormone Receptor-Positive and HER2/Neu Negative (S1207)
Closed
HER2- Positive Breast Cancer, Brain Metastasis (RTOG 1119)
Closed
High Risk, Node-Positive, Early Stage (NSABP B-58)
Closed
Post-Mastectomy and Post-Lumpectomy; Positive Axillary Nodes (NSABP B-51)
Closed
Post Mastectomy Radiation w/Breast Reconstruction (A221505)
Closed
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial (A011801)
Accepting Participants
Solid Tumors, Blood Sample Collection to Evaluate Biomarkers (2018-01)
Closed
Stage I-II Breast Cancer, MRI and Mammography Before Surgery (A011104)
Closed
Triple Negative Breast Cancer (RX-5902)
Complete
Triple-Negative, Node-Positive or High-Risk Node-Negative (NRG-BR003)
Closed
Triple Receptor-Negative Breast Cancer (S1418/BR006)
Closed
Triple-Negative Basal-Like Breast Cancer (EA1131)
Closed
Weight Loss - Breast Cancer (A011401) (BWEL)
In Progress
FDG PET to Assess Therapeutic Response in Patients with Bone-dominant Metastatic Breast Cancer, FEATURE (EA1183)
Closed
A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer (S1706)
Closed
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/NSABP B-63)
Accepting Participants
Ribociclib vs. Palbociclib in Patients With Advanced Breast Cancer Within the HER2-Enriched Intrinsic Subtype (AFT-58)
Accepting Participants
A Phase II Trial of Sacituzumab Govitecan (IMMU-132) (NSC #820016) for Patients With HER2-Negative Breast Cancer and Brain Metastases (S2007)
Accepting Participants
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy (NSABP B-62 CAMBRIA-1)
Accepting Participants
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25 (NRG BR009)
Accepting Participants
Study of ORIC-114 in Patients with Advanced Solid Tumors Harboring an EGFR or HER2 Alteration (ORIC 114-01)
Accepting Participants
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer (CCTG MA.39)
Accepting Participants

Symptom Management & Cancer Control

Randomized Placebo Controlled Trial of Bupropion For Cancer Related Fatigue (URCC 18007)
Accepting Participants
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors (NRG-CC011)
Accepting Participants

Oncology

Screening Mammogram (TMIST) (EA1151)
Accepting Participants

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